Issue
When you are validating on a control, image, or pixel and performing a call to action (mouse click on the validation location - x, y coordinates) you may experience a mouse click offset. When you perform a control validation you will see the red overlay, indicating which control you selected, is out of scope with the underlying control.
Solution
The solution for this issue is setting a fixed resolution when using the LoadGen Studio via a Remote Desktop connection. Also, check the scaling of your machines, make sure this is set to 100%. 